Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9035324 | 0.99 | SETD7 (0.58) | SETD7ALDH1A1SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL9035086 | 0.90 | SETD7 (0.54) | SETD7ALDH1A1SLC6A4SLC6A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL7218948 | 0.89 | SETD7 (0.53) | SETD7ALDH1A1SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL9718770 | 0.87 | SETD7 (0.64) | SETD7ALDH1A1SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL9035949 | 0.87 | SETD7 (0.57) | SETD7ALDH1A1SLC6A4SLC6A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL9718790 | 0.86 | SETD7 (0.62) | SETD7ALDH1A1SLC6A4SLC6A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL7218913 | 0.86 | KMT2A (0.57) | SETD7ALDH1A1SLC6A4SLC6A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL9034034 | 0.84 | SETD7 (0.59) | SETD7ALDH1A1SLC6A4SLC6A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL7211736 | 0.83 | SETD7 (0.61) | SETD7ALDH1A1SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL7299134 | 0.81 | SETD7 (0.51) | SETD7ALDH1A1SLC6A4SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371805-B1 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO KK (JP) | 1996-06-26 | — | — | EP | claimed |
| EP-0371805-A2 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 1990-06-06 | — | — | EP | claimed |
| US-20120016124-A1 | SEROTONIN REUPTAKE INHIBITORS | BAYLOR UNIVERSITY (US) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016124-A1 | SEROTONIN REUPTAKE INHIBITORS | HTR2A, HTR2C, HTR1A | SETD7 3067/4885ALDH1A1 969/4885SLC6A4 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.