Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7212583 | 0.99 | ALDH1A1 (0.50) | SETD7ALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL9035896 | 0.90 | SIGMAR1 (0.54) | SETD7ALDH1A1MAPTCYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL7212711 | 0.89 | SIGMAR1 (0.53) | SETD7ALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL7299683 | 0.88 | SETD7 (0.53) | SETD7ALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL9034437 | 0.87 | SETD7 (0.54) | SETD7ALDH1A1CYP1A2CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL9034533 | 0.87 | SETD7 (0.52) | SETD7ALDH1A1MAPTCYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL7212361 | 0.86 | SETD7 (0.53) | SETD7ALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL9036801 | 0.84 | MAPK1 (0.54) | SETD7ALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL7212545 | 0.82 | SETD7 (0.46) | SETD7ALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL9035696 | 0.81 | SETD7 (0.59) | SETD7ALDH1A1MAPTCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | claimed |
| EP-0371805-B1 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO KK (JP) | 1996-06-26 | — | — | EP | claimed |
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | claimed |
| EP-0371805-A2 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 1990-06-06 | — | — | EP | claimed |
| EP-0479601-B1 | Piperidine derivatives and their use as antiarrhythmic agents | AJINOMOTO KK (JP) | 1999-12-15 | — | — | EP | disclosed |
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | disclosed |
| EP-0479601-A2 | Piperidine derivatives and their use as antiarrhythmic agents | Ajinomoto Co., Inc. (JP) | 1992-04-08 | — | — | EP | disclosed |