Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.54 |
| ▸ | HTR1A | P08908 | 5/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.54 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7218913 | 0.99 | KMT2A (0.57) | SETD7ALDH1A1KMT2AGFERSIGMAR1 | |
| Hydrochloric Acid SCHEMBL9034034 | 0.91 | SETD7 (0.59) | SETD7ALDH1A1KMT2AGFERHTR1A | |
| Hydrochloric Acid SCHEMBL7211736 | 0.90 | SETD7 (0.61) | SETD7ALDH1A1KMT2AGFERSIGMAR1 | |
| SCHEMBL9035562 | 0.90 | SIGMAR1 (0.54) | SETD7ALDH1A1KMT2ASIGMAR1HTR1A | |
| Hydrochloric Acid SCHEMBL7218929 | 0.89 | SIGMAR1 (0.53) | SETD7ALDH1A1KMT2AGFERSIGMAR1 | |
| SCHEMBL9718762 | 0.88 | SETD7 (0.61) | SETD7ALDH1A1KMT2ASIGMAR1HTR1A | |
| SCHEMBL9035696 | 0.87 | SETD7 (0.59) | SETD7ALDH1A1KMT2ASIGMAR1HTR1A | |
| Hydrochloric Acid SCHEMBL9035324 | 0.86 | SETD7 (0.58) | SETD7ALDH1A1KMT2AGFERSIGMAR1 | |
| SCHEMBL11602777 | 0.84 | SETD7 (0.63) | SETD7ALDH1A1KMT2AHTR1ASLC6A4 | |
| SCHEMBL9373592 | 0.83 | DRD2 (0.58) | SETD7KMT2ASIGMAR1HTR1ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371805-B1 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO KK (JP) | 1996-06-26 | — | — | EP | claimed |
| EP-0371805-A2 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 1990-06-06 | — | — | EP | claimed |