Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 8/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.42 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11140434 | 0.87 | L3MBTL1 (0.53) | ALDH1A1MAPTNPSR1L3MBTL1MAPK1 | |
| SCHEMBL21243275 | 0.82 | ALDH1A1 (0.58) | ALDH1A1MPOMAPTNPSR1L3MBTL1 | |
| SCHEMBL24712708 | 0.81 | HRH1 (0.55) | ALDH1A1MAPTNPSR1L3MBTL1MAPK1 | |
| SCHEMBL6200580 | 0.80 | L3MBTL1 (0.56) | ALDH1A1MAPTNPSR1L3MBTL1MAPK1 | |
| SCHEMBL6681802 | 0.77 | L3MBTL1 (0.56) | ALDH1A1MAPTNPSR1L3MBTL1MAPK1 | |
| SCHEMBL24713016 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MPOMAPTNPSR1L3MBTL1 | |
| SCHEMBL4059772 | 0.75 | L3MBTL1 (0.55) | ALDH1A1MAPTNPSR1L3MBTL1MAPK1 | |
| SCHEMBL9038183 | 0.74 | L3MBTL1 (0.53) | ALDH1A1MAPTNPSR1L3MBTL1MAPK1 | |
| SCHEMBL9027053 | 0.74 | ALDH1A1 (0.57) | ALDH1A1MAPTNPSR1L3MBTL1MAPK1 | |
| SCHEMBL6682611 | 0.74 | THRB (0.55) | ALDH1A1MAPTNPSR1L3MBTL1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450066-B1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5401740-A | FOR INHIBITING PLATELET AGGREGATION | OTSUKA PHARMACEUTICAL CO. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5227381-A | Anticoagulant | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |