Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15979699 | 0.75 | DAO (0.63) | DAOKMT2AMEN1ALDH1A1GSK3B | |
| SCHEMBL9034933 | 0.75 | KMT2A (0.69) | KMT2AMEN1ALDH1A1HTTCYP1A2 | |
| SCHEMBL9034210 | 0.72 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1HTTCYP1A2 | |
| SCHEMBL9036006 | 0.71 | MAPT (0.51) | DAOKMT2AMEN1ALDH1A1GSK3B | |
| SCHEMBL28474265 | 0.71 | DAO (0.57) | DAOKMT2AMEN1ALDH1A1GSK3B | |
| SCHEMBL9035245 | 0.70 | KMT2A (0.62) | KMT2AALDH1A1HTR1ALMNAMAPT | |
| SCHEMBL2773258 | 0.70 | DAO (0.55) | DAOGSK3BMAPT | |
| SCHEMBL3867877 | 0.70 | DAO (0.55) | DAOKMT2AMEN1ALDH1A1GSK3B | |
| SCHEMBL6917802 | 0.70 | DAO (0.60) | DAOKMT2AMEN1ALDH1A1HTT | |
| SCHEMBL9036692 | 0.69 | HTT (0.55) | KMT2AMEN1ALDH1A1HTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411775-B1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZET (HU) | 1996-03-13 | — | — | EP | claimed |
| US-5096902-A | Cerebral antihypoxic action, senile dememtia, Alzheimer's, cognitive functions | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1992-03-17 | — | — | US | claimed |
| EP-0411775-A1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-06 | — | — | EP | claimed |
| EP-0411775-B1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZET (HU) | 1996-03-13 | — | — | EP | disclosed |
| US-5096902-A | Cerebral antihypoxic action, senile dememtia, Alzheimer's, cognitive functions | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1992-03-17 | — | — | US | disclosed |
| EP-0411775-A1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-06 | — | — | EP | disclosed |