Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.55 |
| ▸ | HTR1A | P08908 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9036283 | 0.91 | ALDH1A1 (0.52) | KMT2AALDH1A1GFERMAPTSIGMAR1 | |
| SCHEMBL31093179 | 0.90 | KMT2A (0.71) | KMT2AALDH1A1GFERMAPTSIGMAR1 | |
| SCHEMBL9035205 | 0.85 | SIGMAR1 (0.54) | KMT2ASIGMAR1HTR1ASLC6A4SLC6A3 | |
| SCHEMBL9034385 | 0.85 | ALDH1A1 (0.61) | KMT2AALDH1A1MAPTSIGMAR1HTR1A | |
| SCHEMBL9035090 | 0.85 | KMT2A (0.59) | KMT2AALDH1A1GFERMAPTSIGMAR1 | |
| SCHEMBL9036691 | 0.84 | ALDH1A1 (0.55) | KMT2AALDH1A1GFERMAPTLMNA | |
| SCHEMBL9035786 | 0.83 | ALDH1A1 (0.57) | KMT2AALDH1A1GFERMAPTSIGMAR1 | |
| SCHEMBL9035735 | 0.81 | ALDH1A1 (0.42) | KMT2AALDH1A1GFERMAPTLMNA | |
| SCHEMBL16026463 | 0.81 | KMT2A (0.83) | KMT2AALDH1A1GFERMAPTSIGMAR1 | |
| SCHEMBL9035941 | 0.80 | KMT2A (0.51) | KMT2AALDH1A1GFERMAPTHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411775-B1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZET (HU) | 1996-03-13 | — | — | EP | claimed |
| US-5096902-A | Cerebral antihypoxic action, senile dememtia, Alzheimer's, cognitive functions | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1992-03-17 | — | — | US | claimed |
| EP-0411775-A1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-06 | — | — | EP | claimed |
| JP-3048670-A | — | — | None | — | — | JP | disclosed |
| EP-0411775-B1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZET (HU) | 1996-03-13 | — | — | EP | disclosed |
| US-5096902-A | Cerebral antihypoxic action, senile dememtia, Alzheimer's, cognitive functions | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1992-03-17 | — | — | US | disclosed |
| JP-H0348670-A | NITROGEN AND SULFUR CONTAINING HETEROCYCLIC COMPOUND | RICHTER GEDEON V G RT | 1991-03-01 | — | — | JP | disclosed |
| EP-0411775-A1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-06 | — | — | EP | disclosed |