Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83512 | 0.80 | PDE10A (0.44) | KCNH2GPR84TDP1L3MBTL1 | |
| SCHEMBL7783352 | 0.76 | MAPK8 (0.46) | CYP3A4CYP2D6TLR8MAPK8SOAT1 | |
| SCHEMBL9846525 | 0.75 | CYP3A4 (0.33) | CYP3A4CYP2D6NPC1LMNA | |
| SCHEMBL6193083 | 0.73 | LTA4H (0.47) | KCNH2GPR84GPBAR1L3MBTL1LTA4H | |
| SCHEMBL6918344 | 0.73 | CYP3A4 (0.39) | CYP3A4CYP2D6TLR8MAPK8SOAT1 | |
| SCHEMBL6283547 | 0.71 | NUDT1 (0.57) | TLR8MCHR1 | |
| SCHEMBL12597094 | 0.71 | KCNH2 (0.41) | TLR8KCNH2GPR84TDP1L3MBTL1 | |
| SCHEMBL4266406 | 0.71 | MAPK8 (0.45) | CYP3A4CYP2D6TLR8MAPK8L3MBTL1 | |
| SCHEMBL899234 | 0.71 | KCNH2 (0.55) | TLR8KCNH2GPR84TDP1L3MBTL1 | |
| SCHEMBL28512657 | 0.71 | MCHR1 (0.45) | CYP3A4TLR8KCNH2MCHR1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450066-B1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5401740-A | FOR INHIBITING PLATELET AGGREGATION | OTSUKA PHARMACEUTICAL CO. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5227381-A | Anticoagulant | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |