Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13905068 | 0.82 | BCL2 (0.47) | BCL2SMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL1515871 | 0.82 | AKR1B1 (0.58) | BCL2LMNAHTTALDH1A1MAPT | |
| SCHEMBL30352697 | 0.80 | CTBP2 (0.57) | LMNAALDH1A1TP53L3MBTL1 | |
| SCHEMBL8255903 | 0.80 | BCL2 (0.46) | BCL2SMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL12164760 | 0.80 | BCL2 (0.46) | BCL2SMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL7770954 | 0.80 | BCL2 (0.46) | BCL2SMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL6650513 | 0.80 | BCL2 (0.46) | BCL2SMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL7770956 | 0.80 | LMNA (0.46) | BCL2SMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL17430659 | 0.80 | BCL2 (0.46) | BCL2SMN1; SMN2KMT2ALMNAHTT | |
| Acetic Acid SCHEMBL27734248 | 0.79 | BCL2 (0.56) | BCL2SMN1; SMN2ALDH1A1MAPTPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0362902-B1 | Process and intermediates for beta-lactam antibiotics | HARVARD COLLEGE (US) | 1996-01-17 | — | — | EP | disclosed |
| US-5091525-A | 7beta- 2'-(R)-2'-(p-hydroxyphenyl-2'-amino-acetamido!-3-chloro -3-(1-carbadethiacephem)-4-carboxylic acid | ELI LILLY AND COMPANY (US) | 1992-02-25 | — | — | US | disclosed |
| CN-1015178-B | PROCESS AND INTERMEDIATES FOR BETA-LACTAM ANTIBIOTICS | HARVARD COLLEGE (US) | 1991-12-25 | — | — | CN | disclosed |
| CN-1015103-B | PROCESS FOR PREPARING 3-HALO-1-CARBO-3-CEPHEM-4-CARBOXYLIC ACID AND ITS DERIV. | HARVARD COLLEGE (US) | 1991-12-18 | — | — | CN | disclosed |
| EP-0209352-B1 | PROCESS AND INTERMEDIATES FOR BETA-LACTAM ANTIBIOTICS | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1991-05-02 | — | — | EP | disclosed |
| EP-0211540-B1 | INTERMEDIATES AND PROCESS FOR ANTIBIOTICS | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1990-05-16 | — | — | EP | disclosed |
| EP-0362902-A2 | Process and intermediates for beta-lactam antibiotics | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1990-04-11 | — | — | EP | disclosed |
| US-4870169-A | Intermediates for beta-lactam antibiotics | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1989-09-26 | — | — | US | disclosed |
| US-4820816-A | 3-trifuoromethylsulfonyloxy-substituted 1-carbacephalosporins as intermediates for antibiotics | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1989-04-11 | — | — | US | disclosed |
| US-4778884-A | REACTING TRIFLUOROMETHYLSULFONYLOXY COMPOUND WITH LITHIUM HALIDE IN APROTIC POLAR SOLVENT | PRESIDENT & FELLOWS OF HARVARD COLLEGE (US) | 1988-10-18 | — | — | US | disclosed |
| US-4775752-A | Process and intermediates for beta-lactam antibiotics | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1988-10-04 | — | — | US | disclosed |
| US-4734495-A | Process and intermediates for beta-lactam antibiotics | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1988-03-29 | — | — | US | disclosed |
| US-4673737-A | ANTIBIOTICS/ | HARVARD UNIVERSITY (US) | 1987-06-16 | — | — | US | disclosed |
| US-4665171-A | CARBACEPHALOSPORINS | HARVARD UNIVERSITY (US) | 1987-05-12 | — | — | US | disclosed |
| EP-0211540-A1 | Intermediates and process for antibiotics | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1987-02-25 | — | — | EP | disclosed |
| CN-86105247-A | Antibiotic intermediate and preparation method | — | 1987-02-04 | — | — | CN | disclosed |
| CN-86104783-A | The method for preparing beta-Lactam antibiotics | — | 1987-02-04 | — | — | CN | disclosed |
| EP-0209352-A2 | Process and intermediates for beta-lactam antibiotics | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1987-01-21 | — | — | EP | disclosed |