Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744195 | 0.81 | SMN1; SMN2 (0.55) | — | |
| SCHEMBL29051515 | 0.81 | LMNA (0.47) | KDM4EPKMGPR119LMNATP53 | |
| SCHEMBL29043049 | 0.80 | USP30 (0.48) | KDM4EGPR119LMNATP53 | |
| SCHEMBL29043047 | 0.80 | USP30 (0.48) | KDM4EGPR119LMNATP53 | |
| SCHEMBL1912705 | 0.80 | KDM4E (0.62) | KDM4EPKMGPR119FAAHTGFBR1 | |
| SCHEMBL5228089 | 0.80 | SMN1; SMN2 (0.53) | KDM4E | |
| SCHEMBL2023366 | 0.79 | SMN1; SMN2 (0.72) | KDM4EPKMGPR119LMNA | |
| SCHEMBL8618331 | 0.78 | GPR119 (0.49) | KDM4EPKMGPR119FAAHTGFBR1 | |
| SCHEMBL24664329 | 0.78 | KDM4E (0.60) | KDM4EPKMGPR119TGFBR1 | |
| SCHEMBL985065 | 0.78 | GPR119 (0.55) | KDM4EPKMGPR119LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714295-A4 | — | — | 1996-07-10 | — | — | EP | disclosed |
| EP-0714295-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1996-06-05 | — | — | EP | disclosed |