Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035899 | 1.00 | PARP1 (0.50) | PARP1HTR3AHPGDNPSR1LMNA | |
| SCHEMBL854184 | 0.76 | PARP1 (0.61) | PARP1HTR3ALMNAHSD17B10DRD2 | |
| SCHEMBL401463 | 0.72 | DRD2 (0.50) | PARP1HTR3ANPSR1LMNADRD2 | |
| SCHEMBL9243355 | 0.68 | PARP1 (0.55) | PARP1HTR3AHPGDNPSR1KDM4E | |
| SCHEMBL8824093 | 0.68 | PARP1 (0.55) | PARP1HTR3AHPGDNPSR1KDM4E | |
| SCHEMBL13703739 | 0.67 | PARP1 (0.41) | PARP1HTR3AHPGDLMNAHSD17B10 | |
| SCHEMBL13557122 | 0.67 | PARP1 (0.57) | PARP1HTR3ALMNAHSD17B10DRD2 | |
| SCHEMBL405139 | 0.66 | DRD2 (0.48) | PARP1HTR3AHPGDHSD17B10DRD2 | |
| SCHEMBL8824092 | 0.65 | PARP1 (0.45) | PARP1HTR3AKDM4ERECQL | |
| SCHEMBL8823994 | 0.65 | PARP1 (0.58) | PARP1HTR3ALMNAKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405442-B1 | 4,5-Dihydro-6H-imidazo[4,5,1-ij]quinolin-6-one-6-oxime-O-sulfonic acid derivatives | MOCHIDA PHARM CO LTD (JP) | 1996-09-04 | — | — | EP | claimed |
| EP-0405442-A1 | 4,5-Dihydro-6H-imidazo[4,5,1-ij]quinolin-6-one-6-oxime-O-sulfonic acid derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-02 | — | — | EP | claimed |
| EP-0405442-B1 | 4,5-Dihydro-6H-imidazo[4,5,1-ij]quinolin-6-one-6-oxime-O-sulfonic acid derivatives | MOCHIDA PHARM CO LTD (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5151431-A | Diuretics | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1992-09-29 | — | — | US | disclosed |
| US-5151431-A | Diuretics | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0405442-A1 | 4,5-Dihydro-6H-imidazo[4,5,1-ij]quinolin-6-one-6-oxime-O-sulfonic acid derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-02 | — | — | EP | disclosed |
| EP-0405442-A1 | 4,5-Dihydro-6H-imidazo[4,5,1-ij]quinolin-6-one-6-oxime-O-sulfonic acid derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-02 | — | — | EP | disclosed |