Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | WNT3 | P56703 | 1/20 | 0.36 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | ACE | P12821 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL946514 | 1.00 | MEN1 (0.39) | MEN1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL862733 | 1.00 | MEN1 (0.39) | MEN1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL16584576 | 0.92 | FKBP1A (0.41) | MEN1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL15281912 | 0.92 | FKBP1A (0.41) | MEN1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL8266791 | 0.92 | FKBP1A (0.41) | MEN1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL3366889 | 0.87 | KLK7 (0.34) | MEN1KMT2AALDH1A1FKBP1ACHRM2 | |
| SCHEMBL16082361 | 0.87 | KLK7 (0.34) | MEN1KMT2AALDH1A1FKBP1ACHRM2 | |
| SCHEMBL1372911 | 0.87 | CHRM2 (0.41) | MAPTCHRM2CHRM1CHRM3WNT3 | |
| SCHEMBL713924 | 0.87 | CHRM2 (0.41) | MAPTCHRM2CHRM1CHRM3WNT3 | |
| SCHEMBL30289778 | 0.87 | CHRM2 (0.41) | MAPTCHRM2CHRM1CHRM3WNT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 505 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116466003-A | Separation method of N-Boc-L-pyroglutamic acid ethyl ester enantiomer and application thereof | 广西奕安泰药业有限公司 | 2023-07-21 | — | — | CN | claimed |
| WO-2023002984-A1 | METHOD FOR PRODUCING IMIDAZOLE COMPOUND | 小野薬品工業株式会社 | 2023-01-26 | — | — | WO | claimed |
| CN-217534000-U | BOC-L-pyroglutamic acid ethyl ester feeding storage device | 南京安淮创新药物研究院有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-110498762-B | Synthesis method of (2S,5R) -5- [ (benzyloxy) amino ] -piperidine-2-ethyl formate | 山东安信制药有限公司 | 2020-10-27 | — | — | CN | claimed |
| CN-104628622-A | Preparation method of saxagliptin intermediate | SHANGHAI INST TECHNOLOGY | 2015-05-20 | — | — | CN | claimed |
| US-8809024-B2 | Process for preparing dipeptidyl peptidase IV inhibitors and intermediates therefor | ASTRAZENECA AB (SE) | 2014-08-19 | — | — | US | claimed |
| US-20130204012-A1 | Process For Preparing Dipeptidyl Peptidase IV Inhibitors And Intermediates Therefor | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-08-08 | — | — | US | claimed |
| WO-2013111158-A2 | PROCESS FOR THE PREPARATION OF DPP-IV INHIBITOR | MSN LABORATORIES LIMITED (IN) | 2013-08-01 | — | — | WO | claimed |
| CN-122010942-A | Chemical synthesis method of avibactam sodium | 山东安信制药有限公司 | 2026-05-12 | — | — | CN | disclosed |
| EP-3854786-B1 | METHOD FOR PRODUCING AMINO ACID DERIVATIVES | UBE CORP (JP) | 2026-02-18 | — | — | EP | disclosed |
| EP-4640684-A1 | KRAS G12D INHIBITORS AND USES THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2025-10-29 | — | — | EP | disclosed |
| CN-120794902-A | Synthesis method of (2S, 5R) -5- [ (phenylmethoxy) amino ] -2-piperidinecarboxylic acid ethyl ester oxalate | 青岛华商新耀医药科技有限公司 | 2025-10-17 | — | — | CN | disclosed |
| EP-4551577-A1 | FUSED RING KRAS INHIBITORS FOR TREATING DISEASE | Blossomhill Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| US-12286429-B2 | 5-oxo-1,2,3,5,8,8a-hexahydroindolizine-3-carboxamide derivatives useful as a factor XIa inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2025-04-29 | — | — | US | disclosed |
| US-20040259843-A1 | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) | ABBVIE INC. | 2004-12-23 | — | — | US | disclosed |
| WO-2004052850-A2 | METHODS AND COMPOUNDS PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-06-24 | — | — | WO | disclosed |
| US-20040106826-A1 | Process for synthesizing L--methylene glutamic acid and analogs | BIONUMERIK PHARMACEUTICALS, INC. | 2004-06-03 | — | — | US | disclosed |
| WO-2004039314-A2 | PROCESS FOR SYNTHESIZING L-Y-METHYLENE GLUTAMIC ACID AND ANALOGS | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2004-05-13 | — | — | WO | disclosed |
| US-6395767-B2 | ANTIDIABETIC AGENTS; SAXAGLIPTIN | BRISTOL-MYERS SQUIBB COMPANY | 2002-05-28 | — | — | US | disclosed |
| US-20020019411-A1 | Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method | ASTRAZENECA AB (SE) | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12286429-B2 | 5-oxo-1,2,3,5,8,8a-hexahydroindolizine-3-carboxamide derivatives useful as a factor XIa inhibitors | F11, F12, F13A1 | MEN1 1926/4885KMT2A 983/4885ALDH1A1 2307/4885 |
| US-20040106826-A1 | Process for synthesizing L--methylene glutamic acid and analogs | GLUL, QPCT, RIMKLA | MEN1 661/4885KMT2A 480/4885ALDH1A1 2405/4885 |
| US-20020019411-A1 | Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method | DPP4, DPP3, DPP7 | MEN1 4082/4885KMT2A 4285/4885ALDH1A1 1033/4885 |
| US-20040259843-A1 | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) | DPP4, DPP3, DPP7 | MEN1 3576/4885KMT2A 3404/4885ALDH1A1 2295/4885 |
| US-20130204012-A1 | Process For Preparing Dipeptidyl Peptidase IV Inhibitors And Intermediates Therefor | DNPEP, DPP4, PEPD | MEN1 2318/4885KMT2A 2694/4885ALDH1A1 377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.