Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA7 | P43166 | 4/20 | 0.50 |
| ▸ | CA9 | Q16790 | 4/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4708586 | 0.87 | CES2 (0.67) | CYP3A4HPGDMEN1KMT2ACES2 | |
| SCHEMBL26357 | 0.87 | CES2 (0.67) | CYP3A4HPGDMEN1KMT2ACES2 | |
| SCHEMBL29443438 | 0.87 | CES2 (0.67) | CYP3A4HPGDMEN1KMT2ACES2 | |
| SCHEMBL29443437 | 0.87 | CES2 (0.67) | CYP3A4HPGDMEN1KMT2ACES2 | |
| SCHEMBL2985228 | 0.85 | CES2 (0.64) | CYP3A4HPGDMEN1KMT2ACES2 | |
| SCHEMBL8170161 | 0.83 | CES2 (0.57) | THRBCYP3A4HPGDMEN1KMT2A | |
| Formaldehyde SCHEMBL27610922 | 0.83 | CES2 (0.61) | CYP3A4HPGDMEN1KMT2ACES2 | |
| SCHEMBL105807 | 0.80 | THRB (1.00) | THRBCYP3A4HPGDMEN1KMT2A | |
| SCHEMBL1614722 | 0.79 | MEN1 (0.61) | THRBCYP3A4HPGDMEN1KMT2A | |
| Acetophenone SCHEMBL11254057 | 0.79 | KMT2A (0.66) | THRBCYP3A4HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716088-A1 | PROCESS FOR PRODUCING 2-(TETRAZOL-5-YL)-4-OXO-4H-BENZOPYRANS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-12 | — | — | EP | disclosed |