Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | LPO | P22079 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27386804 | 0.83 | CNR2 (0.40) | ALDH1A1CNR2LPOPKMSMN1; SMN2 | |
| SCHEMBL8773424 | 0.79 | ALDH1A1 (0.48) | ALDH1A1IDH1CYP1A2CYP2C19SMN1; SMN2 | |
| Acetic Acid SCHEMBL30330254 | 0.77 | ALDH1A1 (0.39) | ALDH1A1CYP1A2CYP2C19PKMSMN1; SMN2 | |
| SCHEMBL11359814 | 0.76 | RAPGEF4 (0.33) | ALDH1A1LPOKDM4EHPGDMEN1 | |
| SCHEMBL9036331 | 0.75 | ALDH1A1 (0.44) | ALDH1A1IDH1CNR2CYP1A2CYP2C19 | |
| SCHEMBL9031656 | 0.75 | MAPT (0.46) | ALDH1A1LPOPKMSMN1; SMN2HSD17B10 | |
| Ethyl Acetate SCHEMBL27387357 | 0.75 | ALDH1A1 (0.47) | ALDH1A1CNR2LPOCYP1A2SMN1; SMN2 | |
| SCHEMBL387516 | 0.74 | TAAR1 (0.32) | ALDH1A1PKMSMN1; SMN2LMNAMAPT | |
| SCHEMBL29425673 | 0.74 | ALDH1A1 (0.44) | ALDH1A1CYP1A2PKMSMN1; SMN2LMNA | |
| SCHEMBL11352735 | 0.73 | PTGS2 (0.46) | ALDH1A1LMNAHSD17B10KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450066-B1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5401740-A | FOR INHIBITING PLATELET AGGREGATION | OTSUKA PHARMACEUTICAL CO. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5227381-A | Anticoagulant | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0450066-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-09 | — | — | EP | disclosed |