Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 9/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
| ▸ | GABRE | P78334 | 1/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035552 | 0.95 | KCNH2 (0.49) | CCR2DRD3DRD2DRD4KCNH2 | |
| SCHEMBL9034447 | 0.90 | ADRA1D (0.50) | CCR2DRD2KCNH2HTR1AHTR1B | |
| SCHEMBL9033599 | 0.90 | CCR2 (0.47) | CCR2DRD3DRD2HTR1A | |
| SCHEMBL9033135 | 0.90 | CCR2 (0.49) | CCR2 | |
| SCHEMBL9035293 | 0.89 | CCR2 (0.49) | CCR2DRD2HTR1B | |
| SCHEMBL9033156 | 0.88 | CCR2 (0.50) | CCR2DRD2KCNH2HTR1AHTR1B | |
| SCHEMBL9035018 | 0.87 | CCR2 (0.44) | CCR2DRD3DRD2HTR1AHTR1B | |
| SCHEMBL9034903 | 0.87 | CCR2 (0.53) | CCR2DRD3DRD2HTR1A | |
| SCHEMBL8878843 | 0.86 | CCR2 (0.54) | CCR2DRD3DRD2DRD4KCNH2 | |
| SCHEMBL9034812 | 0.86 | CCR2 (0.50) | CCR2DRD2HTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722942-A1 | Indole piperidine derivatives | MERCK PATENT GmbH (DE) | 1996-07-24 | — | — | EP | disclosed |