Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 10/20 | 0.47 |
| ▸ | HTR2C | P28335 | 6/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035205 | 0.85 | SIGMAR1 (0.54) | TSHRKDM4EHTTSMN1; SMN2KCNH2 | |
| SCHEMBL9036691 | 0.84 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2HTR2AHTR2CKCNH2 | |
| SCHEMBL9871356 | 0.78 | ALDH1A1 (0.61) | ALDH1A1TSHRKDM4EHTTSMN1; SMN2 | |
| SCHEMBL28197149 | 0.77 | ALDH1A1 (0.62) | ALDH1A1TSHRKDM4EHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10369554 | 0.77 | ALDH1A1 (0.60) | ALDH1A1TSHRKDM4EHTTSMN1; SMN2 | |
| SCHEMBL9036253 | 0.77 | SIGMAR1 (0.52) | ALDH1A1TSHRHTTSMN1; SMN2KCNH2 | |
| SCHEMBL28197772 | 0.76 | ALDH1A1 (0.58) | ALDH1A1TSHRKDM4EHTTSMN1; SMN2 | |
| SCHEMBL2548153 | 0.74 | ALDH1A1 (0.57) | ALDH1A1TSHRKDM4EHTTSMN1; SMN2 | |
| SCHEMBL10368830 | 0.74 | ATM (0.61) | ALDH1A1TSHRKDM4EHTTSMN1; SMN2 | |
| SCHEMBL9660142 | 0.74 | TSHR (0.68) | ALDH1A1TSHRKDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411775-B1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZET (HU) | 1996-03-13 | — | — | EP | disclosed |
| US-5096902-A | Cerebral antihypoxic action, senile dememtia, Alzheimer's, cognitive functions | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1992-03-17 | — | — | US | disclosed |
| EP-0411775-A1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-06 | — | — | EP | disclosed |