Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035205 | 0.92 | SIGMAR1 (0.54) | SIGMAR1HTR1ATSHRKMT2ADRD2 | |
| SCHEMBL9035786 | 0.84 | ALDH1A1 (0.57) | SIGMAR1HTR1AKMT2AALDH1A1GFER | |
| SCHEMBL7350313 | 0.84 | ALDH1A1 (0.68) | SIGMAR1HTR1ATSHRKMT2AALDH1A1 | |
| SCHEMBL11755100 | 0.82 | ALDH1A1 (0.71) | SIGMAR1HTR1ATSHRKMT2AALDH1A1 | |
| SCHEMBL9034385 | 0.77 | ALDH1A1 (0.61) | SIGMAR1HTR1ATSHRKMT2AALDH1A1 | |
| SCHEMBL9035090 | 0.77 | KMT2A (0.59) | SIGMAR1HTR1ATSHRKMT2AALDH1A1 | |
| SCHEMBL9036736 | 0.77 | ALDH1A1 (0.51) | SIGMAR1TSHRKMT2AALDH1A1DRD2 | |
| SCHEMBL9035245 | 0.77 | KMT2A (0.62) | SIGMAR1HTR1AKMT2AALDH1A1GFER | |
| SCHEMBL9035941 | 0.76 | KMT2A (0.51) | HTR1ATSHRKMT2AALDH1A1GFER | |
| SCHEMBL9036283 | 0.75 | ALDH1A1 (0.52) | SIGMAR1HTR1AKMT2AALDH1A1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411775-B1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZET (HU) | 1996-03-13 | — | — | EP | disclosed |
| US-5096902-A | Cerebral antihypoxic action, senile dememtia, Alzheimer's, cognitive functions | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1992-03-17 | — | — | US | disclosed |
| EP-0411775-A1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-06 | — | — | EP | disclosed |