Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.64 |
| ▸ | TTR | P02766 | 3/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261338 | 0.91 | FFAR1 (0.57) | FFAR1TTR | |
| SCHEMBL9036833 | 0.87 | FFAR1 (0.74) | FFAR1TTRMRGPRX4CHRM1NR3C1 | |
| SCHEMBL2367221 | 0.82 | POLB (0.56) | POLB | |
| SCHEMBL1283828 | 0.80 | FFAR1 (0.57) | FFAR1TTRMRGPRX4TDP1 | |
| SCHEMBL27603203 | 0.80 | FFAR1 (0.57) | FFAR1TTRMRGPRX4CHRM1TDP1 | |
| SCHEMBL4414860 | 0.80 | FFAR1 (0.60) | FFAR1TTRTDP1 | |
| SCHEMBL9270286 | 0.78 | CARM1 (0.53) | POLB | |
| SCHEMBL12667945 | 0.78 | FFAR1 (1.00) | FFAR1TTRMRGPRX4CHRM1TDP1 | |
| SCHEMBL9267107 | 0.78 | LPAR1 (0.48) | FFAR1POLB | |
| SCHEMBL5324430 | 0.77 | FFAR1 (0.61) | FFAR1TTRMRGPRX4NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5403934-A | Heterocyclic compounds | BURROUGHS WELLCOME CO. (US) | 1995-04-04 | — | — | US | disclosed |
| WO-1991013873-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-19 | — | — | WO | disclosed |
| EP-0447164-A1 | Heterocyclic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-18 | — | — | EP | disclosed |