SCHEMBL9036947

SCHEMBL9036947

CCc1nnc2cnc3cc(Cl)c(Cl)cc3n12

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.46
MAPT P10636 1/20 0.37
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GRIA1 P42261 1/20 0.34
GRIA2 P42262 1/20 0.34
GRIA3 P42263 1/20 0.34
GRIA4 P48058 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34
GRIN2B Q13224 1/20 0.34
GRIN2C Q14957 1/20 0.34
GRIN3A Q8TCU5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9036696 0.88 GRIN2D (0.46) POLBMAPTGRIN2DGRIN3BGRIA1
SCHEMBL9037233 0.86 AGTR1 (0.40) POLBMAPTGRIN2DGRIN3BGRIA1
SCHEMBL9037537 0.80 BRD4 (0.37)
SCHEMBL9040622 0.73 ALDH1A1 (0.36)
SCHEMBL10845609 0.73 GRIN2D (0.42) GRIN2DGRIN3BGRIA1GRIA2GRIA3
SCHEMBL9036533 0.71 ABL1 (0.44) POLBMAPT
SCHEMBL10844812 0.71
SCHEMBL10846454 0.69
SCHEMBL10846947 0.66
SCHEMBL11874915 0.65 CUL4A (0.36) POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117795016-A Resin composition, resin sheet, prepreg, metal foil-clad laminate, and printed wiring board 三菱瓦斯化学株式会社 2024-03-29 CN disclosed
EP-0518530-B1 Improvements in or relating to excitatory amino acid receptor antagonists LILLY CO ELI (US) 1996-10-09 EP disclosed
US-5196421-A Treatment of neurological disorders ELI LILLY AND COMPANY (US) 1993-03-23 US disclosed
EP-0518530-A2 Improvements in or relating to excitatory amino acid receptor antagonists ELI LILLY AND COMPANY (US) 1992-12-16 EP disclosed
US-5153196-A Administering for reduction of neurotransmission in nervous system disorders ELI LILLY AND COMPANY (US) 1992-10-06 US disclosed
US-5138000-A High strength molding material CIBA-GEIGY CORPORATION (US) 1992-08-11 US disclosed
US-4264531-A Liquid, linear phosphazene prepolymers and process for preparing same ETHYL CORPORATION (US) 1981-04-28 US disclosed