Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6961986 | 0.87 | KDM1A (0.50) | KDM1AHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL6961976 | 0.80 | TRPV1 (0.55) | KDM1AHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL8012743 | 0.74 | TRPV1 (0.81) | KDM1AHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL6961827 | 0.73 | KDM1A (0.68) | KDM1AHDAC1HDAC2HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL8392010 | 0.72 | KDM1A (0.66) | KDM1AHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL20508341 | 0.70 | HDAC1 (0.69) | KDM1AHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL9036996 | 0.70 | MAPT (0.43) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL31203339 | 0.69 | HDAC1 (0.71) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL19501635 | 0.69 | TRPV1 (0.77) | KDM1AHDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL7636110 | 0.69 | TRPV1 (0.77) | KDM1AHDAC1HDAC2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713483-A1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | Astra Aktiebolag (SE) | 1996-05-29 | — | — | EP | claimed |