Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.57 |
| ▸ | HTR2A | P28223 | 5/20 | 0.51 |
| ▸ | DRD4 | P21917 | 3/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7989995 | 0.99 | DRD2 (0.56) | DRD2SLC6A4HTR2ADRD4SLC6A2 | |
| Maleic Acid SCHEMBL9038026 | 0.93 | DRD2 (0.50) | DRD2SLC6A4HTR2ADRD4SLC6A2 | |
| Fumaric Acid SCHEMBL9038029 | 0.93 | DRD2 (0.50) | DRD2SLC6A4HTR2ADRD4SLC6A2 | |
| Fumaric Acid SCHEMBL7990174 | 0.74 | DRD2 (0.51) | DRD2SLC6A4HTR2ADRD4DRD3 | |
| Maleic Acid SCHEMBL7990173 | 0.74 | DRD2 (0.51) | DRD2SLC6A4HTR2ADRD4DRD3 | |
| SCHEMBL11877556 | 0.72 | SLC6A4 (0.70) | DRD2SLC6A4HTR2ASLC6A2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7979099 | 0.71 | HTR1A (0.57) | DRD2SLC6A4HTR2ASLC6A2HTR7 | |
| SCHEMBL11875197 | 0.70 | SLC6A4 (0.71) | DRD2SLC6A4SLC6A2HTR1A | |
| SCHEMBL9298831 | 0.69 | DRD4 (0.54) | HTR2ADRD4 | |
| Hydrochloric Acid SCHEMBL11877675 | 0.69 | SLC6A4 (0.69) | DRD2SLC6A4SLC6A2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699675-A2 | 3-(4-(1-Substituted-4-piperazinyl)butyl)-4-thiazolidinone and related compounds | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1996-03-06 | — | — | EP | disclosed |