Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | MDH1 | P40925 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | RBP4 | P02753 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038421 | 0.93 | ADRA2A (0.48) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL9038541 | 0.93 | ADRA2A (0.48) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL8985918 | 0.89 | ALDH1A1 (0.52) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL9038780 | 0.89 | ADRA2A (0.49) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL9038172 | 0.89 | PARP1 (0.48) | RBP4KDM4EALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL9037325 | 0.86 | ADRA2A (0.48) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL9036267 | 0.86 | ADRA2A (0.53) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL8985916 | 0.86 | ADRA2A (0.53) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL9037801 | 0.85 | GFER (0.55) | ADRA2AADORA3CHRM1MAOATBXA2R | |
| SCHEMBL9036400 | 0.85 | ADRA2A (0.53) | ADRA2AADORA3CHRM1MAOATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507861-B1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS | UPJOHN CO (US) | 1996-09-11 | — | — | EP | claimed |