Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ARG1 | P05089 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038558 | 0.82 | GLA (0.60) | GLAALDH1A1MAPK1L3MBTL1HTR2C | |
| SCHEMBL9060376 | 0.78 | GLA (0.59) | GLAALDH1A1MAPK1L3MBTL1TSHR | |
| SCHEMBL25179142 | 0.78 | ALDH1A1 (0.50) | GLAALDH1A1MAPK1L3MBTL1NPC1 | |
| SCHEMBL12869925 | 0.77 | ALDH1A1 (0.49) | GLAALDH1A1MAPK1L3MBTL1NPC1 | |
| Trifluoroacetic Acid SCHEMBL9037494 | 0.76 | GLA (0.53) | GLAALDH1A1MAPK1L3MBTL1KMT2A | |
| SCHEMBL27819059 | 0.75 | GLA (0.49) | GLAALDH1A1MAPK1L3MBTL1HTR2C | |
| SCHEMBL8948696 | 0.75 | KMT2A (0.51) | GLAALDH1A1MAPK1L3MBTL1HTR2C | |
| SCHEMBL11063204 | 0.75 | GLA (0.48) | GLAALDH1A1MAPK1L3MBTL1HTR2C | |
| SCHEMBL11464612 | 0.75 | ALDH1A1 (0.50) | GLAALDH1A1MAPK1L3MBTL1HTR2C | |
| SCHEMBL17391044 | 0.75 | ALDH1A1 (0.53) | GLAALDH1A1MAPK1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109219606-A | The piperidines that the halogen of orexin receptor regulator replaces | 阿斯利康(瑞典)有限公司 | 2019-01-15 | — | — | CN | disclosed |