Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.43 |
| ▸ | CDK4 | P11802 | 4/20 | 0.38 |
| ▸ | CCND1 | P24385 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 2/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038237 | 0.88 | CDK4 (0.41) | KDRCDK4CCND1ALDH1A1KMT2A | |
| SCHEMBL9038042 | 0.88 | KDR (0.46) | KDRCDK4CCND1MTNR1AMTNR1B | |
| SCHEMBL9037181 | 0.83 | KDR (0.45) | KDRCDK4CCND1MTNR1AMTNR1B | |
| SCHEMBL9037383 | 0.83 | HTR2C (0.41) | KDRCDK4CCND1ALDH1A1KMT2A | |
| SCHEMBL9036372 | 0.83 | HTR2C (0.41) | KDRCDK4CCND1ALDH1A1KMT2A | |
| SCHEMBL9689717 | 0.83 | CDK4 (0.40) | KDRCDK4CCND1KDM4EMPO | |
| SCHEMBL9038031 | 0.82 | HTR2C (0.41) | KDRCDK4CCND1 | |
| SCHEMBL8985769 | 0.81 | CDK4 (0.39) | KDRCDK4CCND1POLBTDP1 | |
| SCHEMBL9038843 | 0.76 | LMNA (0.39) | KDRCDK4CCND1POLBGAA | |
| SCHEMBL9037086 | 0.76 | CDK4 (0.42) | KDRCDK4CCND1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507861-B1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS | UPJOHN CO (US) | 1996-09-11 | — | — | EP | claimed |
| WO-1991009849-A1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | claimed |