Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 6/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | RRM1 | P23921 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903792 | 0.86 | MAOB (0.62) | KMT2AMEN1MAOBALOX5LMNA | |
| SCHEMBL31185919 | 0.86 | RRM1 (0.53) | KMT2AMEN1MAOBALOX5RRM1 | |
| SCHEMBL4674930 | 0.84 | MEN1 (0.70) | KMT2AMEN1MAOBALOX5LMNA | |
| SCHEMBL8762019 | 0.83 | LMNA (0.60) | MAOBALOX5LMNACYP1A2PTGS1 | |
| SCHEMBL10477886 | 0.82 | KMT2A (0.51) | KMT2AMEN1MAOBALOX5RRM1 | |
| SCHEMBL26563983 | 0.81 | KMT2A (0.59) | KMT2AMEN1MAOBALOX5RRM1 | |
| SCHEMBL13840614 | 0.80 | KMT2A (0.53) | KMT2AMEN1MAOBALOX5RRM1 | |
| SCHEMBL3923237 | 0.80 | KMT2A (0.53) | KMT2AMEN1MAOBALOX5RRM1 | |
| SCHEMBL18655367 | 0.80 | RRM1 (0.51) | KMT2AMEN1MAOBALOX5RRM1 | |
| SCHEMBL31185833 | 0.79 | RRM1 (0.57) | KMT2AMEN1MAOBALOX5RRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041014-A1 | TETRACYCLIC INDOLE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |