Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733470 | 0.87 | MAOB (0.58) | MAOBKMT2ASMN1; SMN2SGMS2BCHE | |
| SCHEMBL4162550 | 0.87 | SMN1; SMN2 (0.59) | MAOBKMT2ASMN1; SMN2SGMS2BCHE | |
| SCHEMBL903779 | 0.86 | KMT2A (0.54) | MAOBKMT2ASMN1; SMN2SGMS2BCHE | |
| SCHEMBL19065075 | 0.84 | MAOB (0.55) | MAOBKMT2ASMN1; SMN2SGMS2BCHE | |
| SCHEMBL16432400 | 0.83 | MAOB (0.57) | MAOBKMT2ASMN1; SMN2SGMS2BCHE | |
| SCHEMBL684282 | 0.83 | MAOB (0.62) | MAOBKMT2ASMN1; SMN2SGMS2BCHE | |
| SCHEMBL5772666 | 0.83 | SMN1; SMN2 (0.67) | MAOBKMT2ASMN1; SMN2SGMS2BCHE | |
| SCHEMBL19415790 | 0.83 | SMN1; SMN2 (0.67) | MAOBKMT2ASMN1; SMN2SGMS2BCHE | |
| SCHEMBL5772077 | 0.83 | KMT2A (0.62) | MAOBKMT2ASMN1; SMN2SGMS2BCHE | |
| SCHEMBL29216490 | 0.83 | KMT2A (0.58) | MAOBKMT2ASMN1; SMN2SGMS2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041014-A1 | TETRACYCLIC INDOLE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |