Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.55 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19400889 | 0.84 | NPC1 (0.73) | CA12CYP1A2CYP3A4ATMCA9 | |
| SCHEMBL31689615 | 0.80 | CA12 (0.63) | CA12CYP1A2CYP3A4ATMCA9 | |
| SCHEMBL24254522 | 0.80 | CA12 (0.63) | CA12CYP1A2CYP3A4ATMCA9 | |
| SCHEMBL2499052 | 0.80 | PKM (0.69) | CA12CYP1A2CYP3A4ATMCA9 | |
| SCHEMBL29956424 | 0.78 | CA12 (0.60) | CA12CYP1A2CYP3A4ATMCA9 | |
| SCHEMBL16599379 | 0.78 | CA12 (0.60) | CA12CYP1A2CYP3A4ATMCA9 | |
| SCHEMBL117930 | 0.77 | PKM (0.65) | CA12CYP1A2CYP3A4ATMCA9 | |
| SCHEMBL19197973 | 0.77 | SMN1; SMN2 (0.69) | CA12CYP1A2CYP3A4ATMCA9 | |
| SCHEMBL198318 | 0.76 | CA12 (1.00) | CA12CYP1A2CYP3A4ATMCA9 | |
| SCHEMBL29230354 | 0.76 | LMNA (0.61) | CA12CA9L3MBTL1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724569-A1 | PROCESS FOR THE PREPARATION OF AN OXIRANE, AZIRIDINE OR CYCLOPROPANE | ZENECA LIMITED (GB) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011230-A1 | PROCESS FOR THE PREPARATION OF AN OXIRANE, AZIRIDINE OR CYCLOPROPANE | ZENECA LIMITED (GB) | 1995-04-27 | — | — | WO | disclosed |