Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17513282 | 0.82 | MEN1 (1.00) | KMT2AMEN1L3MBTL1MAPTPARP1 | |
| SCHEMBL4751480 | 0.79 | MEN1 (0.47) | KMT2AMEN1L3MBTL1MAPTPARP1 | |
| SCHEMBL2278697 | 0.79 | MEN1 (0.70) | KMT2AMEN1L3MBTL1MAPTPARP1 | |
| SCHEMBL9036335 | 0.76 | MEN1 (0.51) | KMT2AMEN1L3MBTL1MAPTPARP1 | |
| SCHEMBL9035419 | 0.76 | ACHE (0.46) | KMT2AMEN1L3MBTL1MAPTPARP1 | |
| SCHEMBL9035160 | 0.74 | KMT2A (0.62) | KMT2AMEN1L3MBTL1MAPTPARP1 | |
| SCHEMBL7038907 | 0.74 | KMT2A (0.41) | KMT2AMEN1L3MBTL1MAPTPARP1 | |
| SCHEMBL6829181 | 0.71 | MAPT (0.64) | KMT2AMEN1L3MBTL1MAPTPARP1 | |
| SCHEMBL7666502 | 0.70 | MEN1 (0.60) | KMT2AMEN1L3MBTL1MAPTPARP1 | |
| SCHEMBL9034184 | 0.70 | MAPT (0.62) | KMT2AMEN1L3MBTL1MAPTPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405442-B1 | 4,5-Dihydro-6H-imidazo[4,5,1-ij]quinolin-6-one-6-oxime-O-sulfonic acid derivatives | MOCHIDA PHARM CO LTD (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5151431-A | Diuretics | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1992-09-29 | — | — | US | disclosed |
| EP-0405442-A1 | 4,5-Dihydro-6H-imidazo[4,5,1-ij]quinolin-6-one-6-oxime-O-sulfonic acid derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1991-01-02 | — | — | EP | disclosed |