Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | RHEB | Q15382 | 4/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | VHL | P40337 | 1/20 | 0.36 |
| ▸ | ELOC | Q15369 | 1/20 | 0.36 |
| ▸ | ELOB | Q15370 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17513282 | 0.76 | MEN1 (1.00) | MEN1KMT2AL3MBTL1MAPTF7 | |
| SCHEMBL2278697 | 0.73 | MEN1 (0.70) | MEN1KMT2AL3MBTL1MAPTF7 | |
| SCHEMBL9037964 | 0.70 | KMT2A (0.70) | MEN1KMT2AL3MBTL1MAPTF7 | |
| SCHEMBL9488215 | 0.70 | RHEB (0.55) | MEN1KMT2AMAPTRHEBGPBAR1 | |
| SCHEMBL6977492 | 0.70 | MEN1 (0.58) | MEN1KMT2AL3MBTL1MAPTF7 | |
| SCHEMBL17750046 | 0.68 | PARP10 (0.67) | MEN1KMT2AL3MBTL1MAPTF7 | |
| SCHEMBL6256563 | 0.66 | MEN1 (0.54) | MEN1KMT2AL3MBTL1MAPTF7 | |
| SCHEMBL9035160 | 0.66 | KMT2A (0.62) | MEN1KMT2AL3MBTL1MAPTF7 | |
| SCHEMBL9034184 | 0.65 | MAPT (0.62) | MEN1KMT2AL3MBTL1MAPTF7 | |
| SCHEMBL23846921 | 0.64 | MEN1 (0.70) | MEN1KMT2AL3MBTL1MAPTF7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |