Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.52 |
| ▸ | HPGD | P15428 | 7/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | FHIT | P49789 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031767 | 0.89 | CYP1A2 (0.45) | ALDH1A1HPGDHSD17B10FHITRAB9A | |
| SCHEMBL27347055 | 0.84 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10FHITRAB9A | |
| SCHEMBL9259408 | 0.81 | FHIT (0.46) | ALDH1A1HPGDHSD17B10FHITRAB9A | |
| SCHEMBL14637700 | 0.74 | FHIT (0.51) | ALDH1A1HPGDHSD17B10FHITRAB9A | |
| SCHEMBL9031215 | 0.74 | FHIT (0.60) | ALDH1A1HPGDHSD17B10FHITRAB9A | |
| SCHEMBL28682112 | 0.70 | GAA (0.44) | ALDH1A1HPGDTSHRMAPK1MAPT | |
| SCHEMBL28692382 | 0.70 | GAA (0.44) | ALDH1A1HPGDTSHRMAPK1MAPT | |
| SCHEMBL14708470 | 0.70 | FHIT (0.74) | ALDH1A1HPGDHSD17B10FHITRAB9A | |
| SCHEMBL14948701 | 0.70 | MAPT (0.69) | ALDH1A1HPGDHSD17B10FHITRAB9A | |
| SCHEMBL22692954 | 0.68 | CYP1A2 (0.54) | ALDH1A1HPGDHSD17B10RAB9ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483683-B1 | Thienoimidazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5463073-A | Angiotensin II antagonists | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0483683-A2 | Thienoimidazole derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1992-05-06 | — | — | EP | disclosed |