Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | FHIT | P49789 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18357933 | 0.91 | KDM4E (0.71) | MAPTRAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL18430421 | 0.89 | ALDH1A1 (0.71) | MAPTRAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL168027 | 0.84 | FHIT (0.61) | MAPTRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL1143421 | 0.81 | MAPT (1.00) | MAPTRAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL28538959 | 0.81 | MAPT (0.65) | MAPTRAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL28907995 | 0.81 | MAPT (0.65) | MAPTRAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL14708470 | 0.81 | FHIT (0.74) | MAPTRAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL9371719 | 0.80 | FHIT (0.57) | MAPTRAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL16896247 | 0.80 | MAPT (0.63) | MAPTRAB9ANPC1ALDH1A1TSHR | |
| SCHEMBL15210472 | 0.79 | MAPT (0.61) | MAPTRAB9ANPC1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9752104-B2 | Thiophene AZO carboxylate dyes and laundry care compositions containing the same | THE PROCTER & GAMBLE COMPANY (US) | 2017-09-05 | — | — | US | disclosed |
| US-9567465-B2 | Thiophene azo carboxylate dyes and laundry care compositions containing the same | MILLIKEN & COMPANY (US) | 2017-02-14 | — | — | US | disclosed |
| US-9556337-B2 | Thiophene azo dyes and laundry care compositions containing the same | MILLIKEN & COMPANY (US) | 2017-01-31 | — | — | US | disclosed |
| US-20160297834-A1 | ACC INHIBITORS AND USES THEREOF | GILEAD APOLLO, LLC | 2016-10-13 | — | — | US | disclosed |
| US-9068081-B2 | Thiophene azo dyes and laundry care compositions containing the same | MILLIKEN & COMPANY (US) | 2015-06-30 | — | — | US | disclosed |
| US-8969557-B2 | ACC inhibitors and uses thereof | Nimbus Apollo, Inc. (US) | 2015-03-03 | — | — | US | disclosed |
| US-8962244-B2 | Compounds for modulating RNA binding proteins and uses therefor | UNIVERSITY OF MASSACHUSETTS (US) | 2015-02-24 | — | — | US | disclosed |
| US-20130217685-A1 | COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR | UNIVERSITY OF MASSACHUSETTS (US) | 2013-08-22 | — | — | US | disclosed |
| US-20130123231-A1 | ACC INHIBITORS AND USES THEREOF | Nimbus Apollo, Inc. (US) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217685-A1 | COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR | TIA1, ZFP3, RBM3 | MAPT 4038/4885RAB9A 2958/4885NPC1 633/4885 |
| US-20130123231-A1 | ACC INHIBITORS AND USES THEREOF | ACACA, ACACB, ACAT2 | MAPT 2490/4885RAB9A 4480/4885NPC1 680/4885 |
| US-20160297834-A1 | ACC INHIBITORS AND USES THEREOF | ACACA, ACACB, ACAT2 | MAPT 2490/4885RAB9A 4480/4885NPC1 680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.