Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038000 | 0.75 | GRM5 (0.41) | UHRF1KDRBCHE | |
| SCHEMBL9039446 | 0.68 | UHRF1 (0.43) | UHRF1KDRBCHE | |
| SCHEMBL20109483 | 0.66 | UHRF1 (0.45) | UHRF1KDR | |
| SCHEMBL15757188 | 0.65 | SCN9A (0.45) | HRH3BCHE | |
| SCHEMBL9038638 | 0.64 | MPO (0.46) | UHRF1KDRBCHE | |
| SCHEMBL15757353 | 0.63 | NUDT1 (0.64) | UHRF1HRH3BCHE | |
| SCHEMBL18292333 | 0.63 | HRH3 (0.56) | KDRHRH3BCHEHRH2ADORA1 | |
| SCHEMBL31712947 | 0.61 | UHRF1 (0.46) | UHRF1BCHE | |
| SCHEMBL12481059 | 0.60 | KDR (0.45) | UHRF1KDRFLT3 | |
| SCHEMBL9851400 | 0.60 | BCHE (0.63) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0495982-B1 | BICYCLIC PYRIMIDINE DERIVATIVE, METHOD OF PRODUCING THE SAME, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LTD (JP) | 1996-06-12 | — | — | EP | disclosed |
| US-5378700-A | Against hypoxemia of respiratory diseases | TEIJIN LIMITED (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0495982-A1 | BICYCLIC PYRIMIDINE DERIVATIVE, METHOD OF PRODUCING THE SAME, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1992-07-29 | — | — | EP | disclosed |