Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 5/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4673773 | 0.79 | SLC6A4 (0.51) | SLC6A4DRD2MTNR1AKDM1AEGFR | |
| SCHEMBL30477104 | 0.76 | SLC6A4 (0.59) | SLC6A4DRD2MTNR1AKDM1ASLC6A2 | |
| SCHEMBL248440 | 0.76 | SLC6A4 (0.59) | SLC6A4DRD2MTNR1AKDM1ASLC6A2 | |
| SCHEMBL7648327 | 0.75 | SLC6A4 (0.44) | SLC6A4DRD2MTNR1AKDM1ASLC6A2 | |
| SCHEMBL7104295 | 0.73 | ADRA1A (0.32) | — | |
| SCHEMBL497994 | 0.72 | SLC6A4 (0.56) | SLC6A4DRD2MTNR1AKDM1ASLC6A2 | |
| SCHEMBL3968194 | 0.72 | SLC6A4 (0.56) | SLC6A4DRD2MTNR1AKDM1ASLC6A2 | |
| SCHEMBL4169706 | 0.71 | SLC18A3 (0.42) | DRD2 | |
| SCHEMBL168782 | 0.71 | SLC6A4 (0.54) | SLC6A4DRD2MTNR1AKDM1ASLC6A2 | |
| SCHEMBL22506964 | 0.71 | HTR2C (0.35) | DRD2SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735024-A1 | Antidepressant N-(Heteroarylaminoalkyl)-4-napthyl substituted piperidines and tetrahydroperidines | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-10-02 | — | — | EP | disclosed |
| US-5472966-A | Antiserotonin agents; side effect reduction | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-12-05 | — | — | US | disclosed |