Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.43 |
| ▸ | GABRP | O00591 | 3/20 | 0.39 |
| ▸ | GABRD | O14764 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.39 |
| ▸ | GABRE | P78334 | 3/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9039634 | 0.85 | KDM4E (0.49) | EEF2KKDM4EKMT2AALDH1A1HPGD | |
| SCHEMBL9039673 | 0.82 | ADORA2A (0.47) | EEF2KADORA2AADORA2BPDE4APDE4B | |
| SCHEMBL9040396 | 0.81 | ADORA2A (0.49) | EEF2KADORA2AADORA2BPDE4APDE4B | |
| SCHEMBL9018998 | 0.80 | ADORA2B (0.48) | EEF2KADORA2AADORA2BPDE4APDE4B | |
| SCHEMBL9037705 | 0.79 | ADORA2A (0.47) | EEF2KADORA2AADORA2BPDE4APDE4B | |
| SCHEMBL9039329 | 0.79 | ADORA2A (0.47) | EEF2KADORA2AADORA2BPDE4APDE4B | |
| SCHEMBL9038553 | 0.77 | ADORA2A (0.43) | EEF2KADORA2AADORA2BPDE4APDE4B | |
| SCHEMBL9039691 | 0.76 | ADORA2A (0.43) | EEF2KADORA2AADORA2BPDE4APDE4B | |
| SCHEMBL9040030 | 0.76 | ADORA2A (0.43) | EEF2KADORA2AADORA2BPDE4APDE4B | |
| SCHEMBL9038167 | 0.76 | ADORA2A (0.43) | EEF2KADORA2AADORA2BPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696590-A1 | Pyrido[2,3-d]pyrimidine derivatives, their preparation and their use as anti-asthma agents | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |