Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EEF2K | O00418 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9038258 | 0.85 | EEF2K (0.46) | KDM4EKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL9018998 | 0.79 | ADORA2B (0.48) | KDM4EALDH1A1HPGDHSD17B10EEF2K | |
| SCHEMBL9039673 | 0.78 | ADORA2A (0.47) | KDM4EALDH1A1HPGDHSD17B10EEF2K | |
| SCHEMBL9040396 | 0.77 | ADORA2A (0.49) | KDM4EALDH1A1HPGDHSD17B10EEF2K | |
| SCHEMBL9039329 | 0.75 | ADORA2A (0.47) | KDM4EALDH1A1HPGDHSD17B10EEF2K | |
| SCHEMBL9037705 | 0.75 | ADORA2A (0.47) | KDM4EALDH1A1HPGDHSD17B10EEF2K | |
| SCHEMBL9038553 | 0.73 | ADORA2A (0.43) | KDM4EALDH1A1HPGDHSD17B10EEF2K | |
| SCHEMBL17433924 | 0.73 | EEF2K (0.45) | KDM4ENPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL9039172 | 0.73 | ALDH1A1 (0.46) | KDM4EKMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL9039691 | 0.72 | ADORA2A (0.43) | KDM4EALDH1A1HPGDHSD17B10EEF2K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696590-A1 | Pyrido[2,3-d]pyrimidine derivatives, their preparation and their use as anti-asthma agents | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |