Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 5/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.40 |
| ▸ | PDE4A | P27815 | 5/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9040616 | 0.77 | ADORA2A (0.41) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL8647860 | 0.77 | ADORA2A (0.41) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL9018998 | 0.73 | ADORA2B (0.48) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL9019089 | 0.73 | ADORA2B (0.44) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL9039917 | 0.72 | ADORA2B (0.40) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL9038401 | 0.69 | ADORA2B (0.40) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL9039738 | 0.68 | ADORA2B (0.40) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL9040396 | 0.66 | ADORA2A (0.49) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL9039673 | 0.64 | ADORA2A (0.47) | ADORA2BADORA2APDE4APDE4BPDE4C | |
| SCHEMBL9038499 | 0.64 | ADORA2A (0.43) | ADORA2BADORA2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696590-A1 | Pyrido[2,3-d]pyrimidine derivatives, their preparation and their use as anti-asthma agents | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |