Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.61 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.60 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.60 |
| ▸ | CTSS | P25774 | 7/20 | 0.59 |
| ▸ | CTSL | P07711 | 3/20 | 0.59 |
| ▸ | CTSB | P07858 | 2/20 | 0.59 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21885556 | 0.90 | CTSK (0.63) | CTSKCAPN1CAPN2CTSSCTSL | |
| SCHEMBL18154376 | 0.90 | CTSK (0.63) | CTSKCAPN1CAPN2CTSSCTSL | |
| SCHEMBL9223452 | 0.88 | CTSS (0.53) | CTSKCAPN1CAPN2CTSSCTSL | |
| SCHEMBL30392055 | 0.88 | CTSS (0.55) | CTSKCTSSCTSLCTSB | |
| SCHEMBL10430509 | 0.88 | CAPN1 (0.66) | CTSKCAPN1CAPN2CTSSCTSL | |
| SCHEMBL23518261 | 0.87 | SYK (0.52) | CTSKCTSSCTSLCTSB | |
| SCHEMBL9215416 | 0.87 | SYK (0.52) | CTSKCTSSCTSLCTSB | |
| SCHEMBL21428920 | 0.87 | CTSK (0.58) | CTSKCAPN1CAPN2CTSSCTSL | |
| SCHEMBL18261742 | 0.87 | CTSS (0.53) | CTSKCAPN1CAPN2CTSSCTSL | |
| SCHEMBL28536287 | 0.87 | CTSS (0.53) | CTSKCAPN1CAPN2CTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491943-A4 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RORER INT HOLDINGS (US) | 1996-02-14 | — | — | EP | disclosed |
| EP-0491943-A1 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-07-01 | — | — | EP | disclosed |
| WO-1992000295-A1 | TETRAHYDROPYRIDOINDOLES AS CHOLECYSTOKININ AND GASTRIN ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-01-09 | — | — | WO | disclosed |