Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23518261 | 1.00 | SYK (0.52) | SYKCTSSKMT2AATMMAPT | |
| SCHEMBL29579283 | 0.93 | MAPT (0.52) | SYKCTSSKMT2AATMMAPT | |
| SCHEMBL19836950 | 0.90 | SYK (0.55) | SYKCTSSKMT2AATMMAPT | |
| SCHEMBL10626940 | 0.90 | SYK (0.55) | SYKCTSSKMT2AATMMAPT | |
| SCHEMBL10308398 | 0.89 | CA2 (0.53) | SYKCTSSKMT2AATMMAPT | |
| SCHEMBL23518454 | 0.89 | SYK (0.50) | SYKCTSSKMT2AATMMAPT | |
| SCHEMBL9038435 | 0.87 | CTSK (0.61) | CTSSCTSKCTSLCTSB | |
| SCHEMBL10448499 | 0.86 | CTSS (0.60) | SYKCTSSKMT2AMAPTCTSK | |
| SCHEMBL30387033 | 0.86 | SYK (0.63) | SYKCTSSMAPTCTSKCTSL | |
| SCHEMBL3955009 | 0.85 | SYK (0.57) | SYKKMT2AMAPTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021119199-A1 | ALPHA-5 BETA-1 INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-06-17 | — | — | WO | disclosed |
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |