Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903920 | 0.86 | GPR119 (0.50) | GPR119 | |
| SCHEMBL10068008 | 0.85 | GPR119 (0.41) | GPR119 | |
| SCHEMBL10068009 | 0.80 | CHRM2 (0.50) | GPR119 | |
| SCHEMBL903955 | 0.78 | GPR119 (0.56) | GPR119 | |
| SCHEMBL3806479 | 0.77 | GPR119 (0.52) | GPR119 | |
| SCHEMBL10067698 | 0.77 | GPR119 (0.45) | GPR119 | |
| SCHEMBL1938312 | 0.76 | GPR119 (0.61) | GPR119 | |
| SCHEMBL14873161 | 0.76 | GPR119 (0.72) | GPR119 | |
| SCHEMBL11946817 | 0.75 | GPR119 (0.77) | GPR119 | |
| SCHEMBL2333408 | 0.75 | GPR119 (0.77) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041158-A1 | TRICYCLIC COMPOUND, PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-04-05 | — | — | WO | disclosed |