Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903960 | 0.85 | GPR119 (0.45) | GPR119 | |
| SCHEMBL10068058 | 0.82 | GPR119 (0.47) | GPR119 | |
| SCHEMBL10067579 | 0.81 | GPR119 (0.38) | GPR119KCNH2 | |
| SCHEMBL903931 | 0.78 | GPR119 (0.35) | GPR119KCNH2OGA | |
| SCHEMBL904171 | 0.78 | GPR119 (0.41) | GPR119KCNH2 | |
| SCHEMBL903941 | 0.75 | GPR119 (0.35) | GPR119KCNH2 | |
| SCHEMBL903940 | 0.74 | GPR119 (0.36) | GPR119KCNH2OGA | |
| SCHEMBL904117 | 0.74 | GPR119 (0.51) | GPR119 | |
| SCHEMBL904116 | 0.74 | GPR119 (0.39) | GPR119KCNH2 | |
| SCHEMBL903971 | 0.74 | CHRNA3 (0.47) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041158-A1 | TRICYCLIC COMPOUND, PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-04-05 | — | — | WO | disclosed |