Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 6/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4417469 | 0.91 | NAAA (0.34) | MEN1KMT2AHTTALDH1A1TSHR | |
| SCHEMBL9334223 | 0.91 | NAAA (0.34) | MEN1KMT2AHTTALDH1A1TSHR | |
| SCHEMBL27491410 | 0.85 | RECQL (0.30) | TSHREPHX2 | |
| SCHEMBL7993979 | 0.84 | DNM1 (0.37) | MEN1KMT2AALDH1A1TSHRNAAA | |
| SCHEMBL7993976 | 0.84 | NAAA (0.31) | NAAA | |
| SCHEMBL15300037 | 0.82 | ALOX5 (0.44) | MEN1KMT2AALDH1A1HSD17B10TSHR | |
| SCHEMBL15299898 | 0.82 | ALOX5 (0.44) | MEN1KMT2AALDH1A1HSD17B10TSHR | |
| SCHEMBL15299864 | 0.82 | ALOX5 (0.44) | MEN1KMT2AALDH1A1HSD17B10TSHR | |
| SCHEMBL15300011 | 0.82 | ALOX5 (0.44) | MEN1KMT2AALDH1A1HSD17B10TSHR | |
| SCHEMBL15299890 | 0.82 | ALOX5 (0.44) | MEN1KMT2AALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0389419-B1 | Non-migrating 1-hydrocarbyloxy hindered amine compounds as polymer stabilizers | CIBA GEIGY AG (CH) | 1996-05-01 | — | — | EP | claimed |
| US-5145893-A | Photostability | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | claimed |
| EP-0389419-A1 | Non-migrating 1-hydrocarbyloxy hindered amine compounds as polymer stabilizers | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | claimed |