Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903835 | 0.88 | GPR119 (0.51) | GPR119 | |
| SCHEMBL10067566 | 0.86 | GPR119 (0.57) | GPR119 | |
| SCHEMBL10067776 | 0.85 | GPR119 (0.48) | GPR119 | |
| SCHEMBL903897 | 0.85 | GPR119 (0.40) | GPR119 | |
| SCHEMBL1938312 | 0.85 | GPR119 (0.61) | GPR119 | |
| SCHEMBL903963 | 0.80 | USP30 (0.47) | GPR119 | |
| SCHEMBL903920 | 0.79 | GPR119 (0.50) | GPR119 | |
| SCHEMBL10068053 | 0.79 | HRH3 (0.39) | — | |
| SCHEMBL903902 | 0.78 | GPR119 (0.45) | GPR119 | |
| SCHEMBL29912881 | 0.77 | GPR119 (0.47) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012041158-A1 | TRICYCLIC COMPOUND, PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | 上海恒瑞医药有限公司 (CN) | 2012-04-05 | — | — | WO | disclosed |