Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8441130 | 0.89 | TXNRD1 (0.38) | LMNAGSRTXNRD1 | |
| SCHEMBL9039383 | 0.87 | TXNRD1 (0.43) | GSRTXNRD1 | |
| SCHEMBL9039829 | 0.78 | — | — | |
| SCHEMBL9037385 | 0.73 | GLP1R (0.33) | — | |
| SCHEMBL5368045 | 0.64 | LMNA (0.44) | LMNALOXL2GSRTXNRD1 | |
| SCHEMBL11817764 | 0.64 | LMNA (0.38) | LMNALOXL2 | |
| SCHEMBL13001461 | 0.63 | — | — | |
| SCHEMBL15526516 | 0.61 | RIPK1 (0.33) | LMNALOXL2 | |
| SCHEMBL10634925 | 0.61 | LMNA (0.39) | LMNALOXL2 | |
| SCHEMBL4565978 | 0.60 | CHRM1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709381-A1 | Heterocyclic compounds and their preparation and use | ELI LILLY AND COMPANY (US) | 1996-05-01 | — | — | EP | claimed |