Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.51 |
| ▸ | NPC1 | O15118 | 8/20 | 0.51 |
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6964818 | 0.75 | HPGD (0.54) | RAB9ANPC1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL9470003 | 0.68 | HPGD (0.63) | RAB9ANPC1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL9038935 | 0.68 | NOS1 (0.49) | — | |
| Iodide SCHEMBL6961838 | 0.67 | NOS1 (0.48) | — | |
| SCHEMBL6965844 | 0.67 | USP2 (0.55) | RAB9ANPC1HPGDSMN1; SMN2LMNA | |
| SCHEMBL9470200 | 0.66 | HPGD (0.59) | RAB9ANPC1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL9079165 | 0.66 | KMT2A (0.65) | RAB9ANPC1HPGDSMN1; SMN2KMT2A | |
| SCHEMBL6119956 | 0.64 | NPC1 (0.65) | RAB9ANPC1HPGDSMN1; SMN2KMT2A | |
| Phenol SCHEMBL28293077 | 0.63 | NPC1 (0.58) | RAB9ANPC1HPGDSMN1; SMN2KMT2A | |
| Benzene SCHEMBL28118471 | 0.62 | ATM (0.63) | RAB9ANPC1HPGDSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713483-A1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | Astra Aktiebolag (SE) | 1996-05-29 | — | — | EP | disclosed |