Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 6/20 | 0.63 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.59 |
| ▸ | HTR2A | P28223 | 2/20 | 0.59 |
| ▸ | HTR7 | P34969 | 2/20 | 0.59 |
| ▸ | HTR6 | P50406 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9470003 | 0.80 | HPGD (0.63) | KMT2AMEN1HPGDRAB9ANPC1 | |
| SCHEMBL27979632 | 0.77 | ALDH1A1 (0.82) | KMT2AMEN1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7279604 | 0.77 | HTR1B (0.65) | KMT2AHPGDTDP1ALDH1A1KDM4E | |
| SCHEMBL29865493 | 0.77 | KDM4E (0.68) | KMT2AHPGDTDP1ALDH1A1KDM4E | |
| SCHEMBL5488944 | 0.77 | KDM4E (0.68) | KMT2AHPGDTDP1ALDH1A1KDM4E | |
| Oxalic Acid SCHEMBL8780050 | 0.77 | HRH3 (0.83) | KMT2AMEN1LMNAHRH3HTR2A | |
| SCHEMBL9470200 | 0.76 | HPGD (0.59) | KMT2AMEN1HPGDRAB9ANPC1 | |
| SCHEMBL14970546 | 0.76 | HRH3 (0.89) | KMT2AMEN1HRH3HTR2AHTR7 | |
| Oxalic Acid SCHEMBL8780098 | 0.75 | TDP1 (0.85) | KMT2AMEN1LMNAHRH3HTR2A | |
| SCHEMBL1377331 | 0.75 | ALDH1A1 (0.61) | HPGDRAB9ASMN1; SMN2LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543422-A | HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS, FUNGICIDES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-08-06 | — | — | US | disclosed |
| EP-0662964-A1 | HETEROCYCLIC AMINES HAVING COLMODULIN ANTAGONIST PROPERTIES. | BRITISH TECH GROUP (GB) | 1995-07-19 | — | — | EP | disclosed |
| WO-1994007875-A1 | HETEROCYCLIC AMINES HAVING COLMODULIN ANTAGONIST PROPERTIES | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-04-14 | — | — | WO | disclosed |