Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9470003 | 0.82 | HPGD (0.63) | HPGDRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL9470013 | 0.79 | PTGDR2 (0.49) | HPGDSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL9470018 | 0.79 | PTGDR2 (0.49) | HPGDSMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL9469512 | 0.77 | KMT2A (0.48) | HPGDRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL9079165 | 0.76 | KMT2A (0.65) | HPGDRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL9469063 | 0.75 | MAPT (0.49) | HPGDRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL9469062 | 0.75 | MAPT (0.49) | HPGDRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL9469663 | 0.73 | LMNA (0.53) | HPGDRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL9469150 | 0.73 | LMNA (0.53) | HPGDRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL9469148 | 0.73 | LMNA (0.53) | HPGDRAB9ANPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5183925-A | LEUKOTRIENE-B4 DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE AS PHARMACEUTICAL AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-02-02 | — | — | US | disclosed |