Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.44 |
| ▸ | PCSK9 | Q8NBP7 | 10/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535072 | 0.85 | UTS2R (0.47) | UTS2RLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9533783 | 0.84 | CYP2D6 (0.48) | UTS2RMAPK1POLB | |
| SCHEMBL9534801 | 0.81 | PIK3CD (0.40) | UTS2RLMNAKMT2AALDH1A1POLB | |
| SCHEMBL9535041 | 0.80 | KDM4E (0.43) | UTS2RLMNAKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9535004 | 0.79 | PIK3CG (0.40) | UTS2RLMNAKMT2AALDH1A1MAPT | |
| SCHEMBL9534796 | 0.76 | LRRK2 (0.42) | MAPK1ALDH1A1POLBMAPT | |
| SCHEMBL9039484 | 0.76 | TAS2R14 (0.46) | PCSK9LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9534736 | 0.73 | PIK3CD (0.43) | LMNAMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL9972896 | 0.71 | PIK3CD (0.41) | LMNAKMT2ASMN1; SMN2HTTALDH1A1 | |
| SCHEMBL9534747 | 0.70 | PIK3CD (0.43) | LMNAKMT2AALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244352-B1 | Pyrido[4,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |
| US-4808618-A | ANTIALLERGENS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1989-02-28 | — | — | US | disclosed |
| EP-0244352-A2 | Pyrido[4,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1987-11-04 | — | — | EP | disclosed |