Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9242285 | 0.80 | ALDH1A1 (0.54) | KMT2AMEN1ALDH1A1TSHRGAA | |
| SCHEMBL9039574 | 0.78 | KMT2A (0.41) | KMT2AALDH1A1CYP2A13MAOBADRA2A | |
| SCHEMBL6548888 | 0.77 | ADRA2A (0.35) | KMT2AMEN1OPRM1OPRD1PTGS1 | |
| SCHEMBL7473519 | 0.77 | CYP2A13 (0.38) | KMT2AALDH1A1TSHRHTTCYP2A13 | |
| SCHEMBL9354355 | 0.74 | CYP2A13 (0.33) | KMT2AOPRM1OPRD1TSHRCYP2A13 | |
| SCHEMBL7562061 | 0.73 | TSHR (0.43) | KMT2AMEN1ALDH1A1TSHRHTT | |
| SCHEMBL7480880 | 0.72 | TSHR (0.56) | KMT2AMEN1ALDH1A1TSHRHTT | |
| SCHEMBL9244012 | 0.72 | TSHR (0.61) | KMT2AMEN1ALDH1A1TSHRHTT | |
| SCHEMBL9240251 | 0.71 | HTT (0.39) | KMT2AALDH1A1TSHRHTTMAOB | |
| SCHEMBL9656558 | 0.71 | KMT2A (0.44) | KMT2AMEN1ALDH1A1TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467851-A1 | Stabilized monomer compositions | CIBA-GEIGY AG (CH) | 1992-01-22 | — | — | EP | claimed |
| EP-0309402-B2 | N-substituted hindered amine stabilizers | CIBA SC HOLDING AG (CH) | 2002-06-12 | — | — | EP | disclosed |
| EP-0309402-B1 | N-substituted hindered amine stabilizers | CIBA GEIGY AG (CH) | 1995-01-11 | — | — | EP | disclosed |
| EP-0389430-B1 | N-hydrocarbyloxy hindered amine light stabilizers substituted with phosphorus moieties | CIBA GEIGY AG (CH) | 1994-10-26 | — | — | EP | disclosed |
| US-5204473-A | O-substituted N-hydroxy hindered amine stabilizers | CIBA-GEIGY CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |
| EP-0467851-A1 | Stabilized monomer compositions | CIBA-GEIGY AG (CH) | 1992-01-22 | — | — | EP | disclosed |
| US-5021481-A | For use with polymers | CIBA-GEIGY CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| EP-0389430-A1 | N-hydrocarbyloxy hindered amine light stabilizers substituted with phosphorus moieties | CIBA-GEIGY AG (CH) | 1990-09-26 | — | — | EP | disclosed |
| EP-0309402-A1 | N-substituted hindered amine stabilizers | CIBA-GEIGY AG (CH) | 1989-03-29 | — | — | EP | disclosed |