Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843188 | 0.86 | NAMPT (0.57) | DHFRNAMPTLMNA | |
| SCHEMBL9042512 | 0.85 | NAMPT (0.43) | DHFRNAMPTLMNARAB9A | |
| SCHEMBL9044536 | 0.84 | NAMPT (0.51) | DHFRNAMPTLMNA | |
| SCHEMBL9040527 | 0.82 | DHFR (0.51) | DHFRL3MBTL1HSD17B10 | |
| SCHEMBL9040512 | 0.82 | DHFR (0.51) | DHFRL3MBTL1HSD17B10 | |
| SCHEMBL9040305 | 0.82 | NAMPT (0.42) | DHFRNAMPTLMNA | |
| SCHEMBL9039740 | 0.81 | DHFR (0.51) | DHFRTDP1L3MBTL1NPC1LMNA | |
| SCHEMBL9044792 | 0.77 | TYMS (0.51) | DHFRNAMPTNPC1LMNARAB9A | |
| SCHEMBL9042706 | 0.76 | DHFR (0.66) | DHFR | |
| SCHEMBL9047680 | 0.76 | DHFR (0.45) | DHFRNAMPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400562-B1 | Pyrrolopyrimidines, their production and use as tumoricidal agents | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-08-21 | — | — | EP | disclosed |