Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6966289 | 0.99 | NPC1 (0.47) | NPC1SMN1; SMN2RAB9AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL6962460 | 0.99 | NPC1 (0.47) | NPC1SMN1; SMN2RAB9AALDH1A1HPGD | |
| SCHEMBL6963560 | 0.90 | GAA (0.49) | NPC1SMN1; SMN2RAB9AALDH1A1CA12 | |
| SCHEMBL6958210 | 0.90 | GAA (0.49) | NPC1SMN1; SMN2RAB9AALDH1A1CA12 | |
| SCHEMBL6962276 | 0.88 | NPC1 (0.52) | NPC1SMN1; SMN2RAB9AALDH1A1CA12 | |
| SCHEMBL4397478 | 0.88 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL27357975 | 0.88 | NOS3 (0.47) | NPC1SMN1; SMN2RAB9AALDH1A1NOS3 | |
| SCHEMBL6969036 | 0.87 | MEN1 (0.52) | NPC1SMN1; SMN2RAB9AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL6961155 | 0.87 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL27489893 | 0.87 | NOS3 (0.47) | NPC1SMN1; SMN2RAB9AALDH1A1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713483-A1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | Astra Aktiebolag (SE) | 1996-05-29 | — | — | EP | claimed |
| WO-1995005363-A1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | ASTRA AKTIEBOLAG (SE) | 1995-02-23 | — | — | WO | claimed |