Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9042267 | 1.00 | ATM (0.37) | ATMKCNH2L3MBTL1SLC2A1ALDH1A1 | |
| SCHEMBL9040600 | 0.88 | ATM (0.36) | ATMKCNH2L3MBTL1SLC2A1ALDH1A1 | |
| SCHEMBL9040595 | 0.88 | ATM (0.36) | ATMKCNH2L3MBTL1SLC2A1ALDH1A1 | |
| SCHEMBL9040751 | 0.85 | AOC3 (0.40) | ATML3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL9040072 | 0.84 | POLB (0.42) | ATML3MBTL1ALDH1A1MAPTPOLB | |
| SCHEMBL9040067 | 0.84 | POLB (0.42) | ATML3MBTL1ALDH1A1MAPTPOLB | |
| SCHEMBL9044938 | 0.83 | POLB (0.39) | POLBNPC1SMN1; SMN2 | |
| SCHEMBL9038821 | 0.83 | MAPT (0.41) | ATML3MBTL1ALDH1A1MAPTPOLB | |
| SCHEMBL9205224 | 0.83 | ALDH1A1 (0.43) | ATMALDH1A1MAPTHPGDCCR5 | |
| SCHEMBL337168 | 0.83 | ALDH1A1 (0.43) | ATMALDH1A1MAPTHPGDCCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442497-B1 | Novel beta-lactam compounds and their production | SUMITOMO PHARMA (JP) | 1996-08-14 | — | — | EP | disclosed |
| US-5227376-A | Quaternary ammonium carbapenem antibiotics | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0442497-A1 | Novel beta-lactam compounds and their production | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-08-21 | — | — | EP | disclosed |